Galidesivir

Galidesivir

SCHEMBL30477706

Cl.Nc1ncnc2c(C3NC(CO)C(O)C3O)c[nH]c12

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

Lrep

The experimentally established mechanism targets of Galidesivir. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PNP P00491 2/20 0.97
MTAP Q13126 16/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Galidesivir SCHEMBL4838048 1.00 PNP (0.97) PNPMTAP
Galidesivir SCHEMBL15525360 1.00 PNP (0.97) PNPMTAP
Galidesivir SCHEMBL29577672 1.00 PNP (0.97) PNPMTAP
Galidesivir SCHEMBL25424734 0.99 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL15717852 0.99 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL16884051 0.99 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL23102311 0.99 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL17760735 0.99 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL12468816 0.99 PNP (1.00) PNPMTAP
Galidesivir SCHEMBL15718263 0.99 PNP (1.00) PNPMTAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023126968-A1 A PROCESS FOR THE SYNTHESIS OF BCX-1777 AND BCX-4430 COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2023-07-06 WO disclosed