Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL7927043 | 0.82 | TDP1 (0.83) | TDP1FFAR3ALDH1A1CES2CES1 | |
| SCHEMBL42679 | 0.82 | — | — | |
| SCHEMBL2357325 | 0.82 | TDP1 (1.00) | TDP1FFAR3ALDH1A1CES2CES1 | |
| SCHEMBL1887087 | 0.82 | — | — | |
| Propionic Acid SCHEMBL28846408 | 0.80 | — | — | |
| Butanone SCHEMBL2241141 | 0.80 | — | — | |
| Propionic Acid SCHEMBL10493407 | 0.80 | FFAR3 (0.67) | TDP1FFAR3ALDH1A1CES2CES1 | |
| SCHEMBL8617909 | 0.79 | — | — | |
| Fluoride SCHEMBL8001538 | 0.78 | TDP1 (0.91) | TDP1FFAR3ALDH1A1CES2CES1 | |
| SCHEMBL7627319 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106047828-B | Carbonyl reductase ChKRED20 mutant and application thereof | 中国科学院成都生物研究所 | 2019-10-08 | — | — | CN | disclosed |
| US-7807341-B2 | Method for forming organic mask and method for forming pattern using said organic mask | NEC LCD TECHNOLOGIES, LTD. (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20050230348-A1 | Method for forming organic mask and method for forming pattern using said organic mask | NEC LCD TECHNOLOGIES, LTD. (JP) | 2005-10-20 | — | — | US | disclosed |