Tartaric Acid

Tartaric Acid

SCHEMBL30478388

CC[C@@H]1CN(C(=O)OC(C)(C)C)C[C@@H]1N.O=C(O)[C@H](O)[C@@H](O)C(=O)O

nearest known ligand 0.56

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Known targets — ChEMBL curated mechanism

ACHEADRA2AADRA2BADRA2CBCHECHRNA4CHRNB2GHSRMAOBUGCG

The experimentally established mechanism targets of Tartaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.43
DPP4 P27487 1/20 0.35
PDE4B Q07343 3/20 0.35
USP2 O75604 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NAMPT P43490 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
RORC P51449 1/20 0.34
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
HPGD P15428 1/20 0.33
GPR119 Q8TDV5 1/20 0.33
JAK3 P52333 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23931069 0.90 NR1H2 (0.50) NR1H2DPP4PDE4BUSP2SMN1; SMN2
SCHEMBL30639835 0.80 NR1H2 (0.56) NR1H2PDE4BUSP2SMN1; SMN2NAMPT
SCHEMBL21670174 0.80 NR1H2 (0.56) NR1H2PDE4BUSP2SMN1; SMN2NAMPT
SCHEMBL376311 0.80 NR1H2 (0.56) NR1H2PDE4BUSP2SMN1; SMN2NAMPT
SCHEMBL31081870 0.80 NR1H2 (0.56) NR1H2PDE4BUSP2SMN1; SMN2NAMPT
SCHEMBL10238539 0.80 NR1H2 (0.56) NR1H2PDE4BUSP2SMN1; SMN2NAMPT
SCHEMBL30639814 0.80 NR1H2 (0.56) NR1H2PDE4BUSP2SMN1; SMN2NAMPT
SCHEMBL21670176 0.80 NR1H2 (0.56) NR1H2PDE4BUSP2SMN1; SMN2NAMPT
SCHEMBL14303506 0.79 NR1H2 (0.57) NR1H2PDE4BUSP2SMN1; SMN2NAMPT
SCHEMBL24126962 0.79 NR1H2 (0.48) NR1H2DPP4PDE4BUSP2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116359360-A Determination analysis method for compound I content in HHT-109 raw material 上海科胜药物研发有限公司 2023-06-30 CN disclosed