Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851599 | 1.00 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2NPC1UCHL1ALDH1A1 | |
| SCHEMBL7851601 | 1.00 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2NPC1UCHL1ALDH1A1 | |
| SCHEMBL5744460 | 0.85 | HSD17B10 (0.48) | HSD17B10SMN1; SMN2NPC1UCHL1ALDH1A1 | |
| SCHEMBL5744462 | 0.85 | HSD17B10 (0.48) | HSD17B10SMN1; SMN2NPC1UCHL1ALDH1A1 | |
| SCHEMBL3612669 | 0.85 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2NPC1UCHL1ALDH1A1 | |
| SCHEMBL19958804 | 0.85 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2NPC1UCHL1ALDH1A1 | |
| SCHEMBL3612674 | 0.85 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2NPC1UCHL1ALDH1A1 | |
| SCHEMBL3604748 | 0.85 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2NPC1UCHL1ALDH1A1 | |
| SCHEMBL15356409 | 0.85 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2NPC1UCHL1ALDH1A1 | |
| SCHEMBL3592625 | 0.85 | HSD17B10 (0.47) | HSD17B10SMN1; SMN2NPC1UCHL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422755-B | Nitrogen-containing heterocyclic compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2023-07-04 | — | — | CN | disclosed |