Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25031324 | 1.00 | CRBN (0.50) | CRBNDDB1POLBALDH1A1ALDH1A3 | |
| SCHEMBL30955798 | 0.86 | CRBN (0.53) | CRBNDDB1POLB | |
| SCHEMBL30475443 | 0.86 | CRBN (0.46) | CRBNDDB1POLBALDH1A1ALDH1A3 | |
| SCHEMBL25031349 | 0.86 | CRBN (0.46) | CRBNDDB1POLBALDH1A1ALDH1A3 | |
| SCHEMBL25935360 | 0.84 | CRBN (0.49) | CRBNDDB1POLB | |
| SCHEMBL30479043 | 0.84 | CRBN (0.49) | CRBNDDB1POLB | |
| SCHEMBL30066283 | 0.84 | CRBN (0.45) | CRBNDDB1POLBALDH1A1 | |
| SCHEMBL24671220 | 0.84 | CRBN (0.45) | CRBNDDB1POLBALDH1A1 | |
| SCHEMBL27194319 | 0.84 | CRBN (0.45) | CRBNDDB1POLBALDH1A1 | |
| SCHEMBL30955788 | 0.79 | DDB1 (0.63) | CRBNDDB1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261458-B | PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116261458-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-13 | — | — | CN | disclosed |