Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25331084 | 1.00 | ESR1 (0.64) | ESR1 | |
| SCHEMBL21947674 | 0.92 | ESR1 (0.75) | ESR1 | |
| SCHEMBL29875575 | 0.92 | ESR1 (0.75) | ESR1 | |
| SCHEMBL25967204 | 0.87 | ESR1 (0.59) | ESR1 | |
| SCHEMBL30479247 | 0.86 | ESR1 (0.57) | ESR1 | |
| SCHEMBL25333542 | 0.86 | ESR1 (0.57) | ESR1 | |
| SCHEMBL25953898 | 0.85 | ESR1 (0.58) | ESR1 | |
| SCHEMBL30823913 | 0.84 | ESR1 (0.64) | ESR1 | |
| SCHEMBL27107806 | 0.84 | ESR1 (0.64) | ESR1 | |
| SCHEMBL23794263 | 0.83 | ESR1 (0.65) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472982-A1 | PROCESSES FOR THE PREPARATION OF SELECTIVE ESTROGEN RECEPTOR DEGRADERS | Eli Lilly and Company (US) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023150056-A1 | PROCESSES FOR THE PREPARATION OF SELECTIVE ESTROGEN RECEPTOR DEGRADERS | ELI LILLY AND COMPANY (US) | 2023-08-10 | — | — | WO | disclosed |