SCHEMBL30479348

SCHEMBL30479348

O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCCC2CCCOC2)cc1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SCN5A Q14524 14/20 1.00
SCN9A Q15858 8/20 0.84
CYP3A4 P08684 7/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20115570 1.00 SCN5A (1.00) SCN5ASCN9ACYP3A4
SCHEMBL30479369 0.91 SCN5A (1.00) SCN5ASCN9ACYP3A4
SCHEMBL20115548 0.91 SCN5A (1.00) SCN5ASCN9ACYP3A4
SCHEMBL30479385 0.90 SCN5A (1.00) SCN5ASCN9ACYP3A4
SCHEMBL20115680 0.90 SCN5A (1.00) SCN5ASCN9ACYP3A4
SCHEMBL30479376 0.90 SCN5A (1.00) SCN5ASCN9ACYP3A4
SCHEMBL20115631 0.90 SCN5A (1.00) SCN5ASCN9ACYP3A4
SCHEMBL30479361 0.86 SCN5A (0.95) SCN5ASCN9ACYP3A4
SCHEMBL20115782 0.86 SCN5A (0.95) SCN5ASCN9ACYP3A4
SCHEMBL30479347 0.86 SCN5A (1.00) SCN5ASCN9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110088093-B Acyl sulfonamide nav1.7 inhibitors 百时美施贵宝公司 2023-06-13 CN disclosed