Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.48 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978516 | 0.96 | PTPN1 (0.49) | PTPN1GRB2MDM4TP53MDM2 | |
| SCHEMBL30590007 | 0.93 | PTPN1 (0.45) | PTPN1GRB2MDM4TP53BACE1 | |
| SCHEMBL30589998 | 0.92 | PTPN1 (0.45) | PTPN1GRB2MDM4TP53 | |
| SCHEMBL30589994 | 0.92 | PTPN1 (0.45) | PTPN1GRB2MDM4TP53 | |
| SCHEMBL30590008 | 0.91 | PTPN1 (0.53) | PTPN1GRB2MDM2 | |
| SCHEMBL29978837 | 0.89 | PTPN1 (0.46) | PTPN1GRB2MDM4TP53BACE1 | |
| SCHEMBL29978246 | 0.89 | PTPN1 (0.46) | PTPN1GRB2MDM4TP53 | |
| SCHEMBL29978024 | 0.87 | PTPN1 (0.54) | PTPN1GRB2MDM4TP53MDM2 | |
| SCHEMBL1770944 | 0.86 | PTPN1 (0.41) | PTPN1GRB2MDM4TP53MDM2 | |
| SCHEMBL1770431 | 0.85 | PTPN1 (0.41) | PTPN1MDM4TP53MDM2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11970551-B2 | Solution phase routes for WNT hexapeptides | WNTRESEARCH AB (SE) | 2024-04-30 | — | — | US | disclosed |
| US-11912791-B2 | Solution phase routes for Wnt hexapeptides | WNTRESEARCH AB (SE) | 2024-02-27 | — | — | US | disclosed |
| US-20230295232-A1 | SOLUTION PHASE ROUTES FOR WNT HEXAPEPTIDES | WNTRESEARCH AB (SE) | 2023-09-21 | — | — | US | disclosed |
| EP-3841107-B1 | SOLUTION PHASE ROUTES FOR WNT HEXAPEPTIDES | WNTRESEARCH AB (SE) | 2023-06-28 | — | — | EP | disclosed |