Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.39 |
| ▸ | XPO1 | O14980 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 9/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL616225 | 1.00 | TET2 (0.40) | TET2OGFOD1TET1EGLN2EGLN1 | |
| SCHEMBL616224 | 1.00 | TET2 (0.40) | TET2OGFOD1TET1EGLN2EGLN1 | |
| SCHEMBL615827 | 0.82 | XPO1 (0.42) | XPO1MEN1LMNAMAPTKMT2A | |
| SCHEMBL30480732 | 0.82 | XPO1 (0.42) | XPO1MEN1LMNAMAPTKMT2A | |
| SCHEMBL615828 | 0.82 | XPO1 (0.42) | XPO1MEN1LMNAMAPTKMT2A | |
| SCHEMBL617054 | 0.82 | NOTUM (0.44) | NOTUMF11KLKB1MEN1LMNA | |
| SCHEMBL617053 | 0.82 | NOTUM (0.44) | NOTUMF11KLKB1MEN1LMNA | |
| SCHEMBL29053527 | 0.81 | XPO1 (0.43) | XPO1F11KLKB1MEN1LMNA | |
| SCHEMBL30194207 | 0.81 | XPO1 (0.43) | XPO1F11KLKB1MEN1LMNA | |
| SCHEMBL29053476 | 0.81 | KMT2A (0.44) | XPO1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107973809-B | Macrocyclic compounds as factor XIA inhibitors | 百时美施贵宝公司 | 2023-06-30 | — | — | CN | disclosed |