Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.56 |
| ▸ | HTR2A | P28223 | 9/20 | 0.56 |
| ▸ | HTR2B | P41595 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18122551 | 1.00 | HTR2C (0.56) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9331130 | 0.94 | HTR2C (0.53) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| SCHEMBL18115471 | 0.90 | HTR2C (0.64) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| SCHEMBL9331292 | 0.89 | HTR2C (0.54) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9331810 | 0.87 | HTR2C (0.53) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| SCHEMBL10912768 | 0.86 | MAPT (0.45) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7373928 | 0.84 | MAPT (0.44) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| SCHEMBL30340758 | 0.81 | MAPT (0.43) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| SCHEMBL5468971 | 0.81 | MAPT (0.43) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| SCHEMBL25405400 | 0.80 | HTR2C (0.47) | HTR2CHTR2AHTR2BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116368128-A | Heterocyclic compounds as CBP/EP300 bromodomain inhibitors | 奥瑞基尼肿瘤有限公司 | 2023-06-30 | — | — | CN | disclosed |