Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30481249 | 1.00 | SCN9A (0.43) | SCN9ACYP19A1PTGS1PTGS2NPBWR1 | |
| SCHEMBL25240651 | 1.00 | SCN9A (0.43) | SCN9ACYP19A1PTGS1PTGS2NPBWR1 | |
| SCHEMBL4794897 | 0.90 | SCN9A (0.48) | SCN9ACYP19A1PTGS1PTGS2NPBWR1 | |
| SCHEMBL4795769 | 0.82 | EGLN2 (0.41) | SCN9APTGS1PTGS2PTGER4 | |
| SCHEMBL30481224 | 0.81 | SSTR5 (0.43) | CYP19A1NPBWR1SSTR5ABCG2 | |
| SCHEMBL30481223 | 0.81 | SSTR5 (0.43) | CYP19A1NPBWR1SSTR5ABCG2 | |
| SCHEMBL25285426 | 0.81 | SSTR5 (0.43) | CYP19A1NPBWR1SSTR5ABCG2 | |
| SCHEMBL25237937 | 0.80 | SCN9A (0.43) | SCN9ACYP19A1PTGS1PTGS2NPBWR1 | |
| SCHEMBL4791493 | 0.80 | SCN9A (0.47) | SCN9AAKR1C3AKR1C2 | |
| SCHEMBL30481231 | 0.80 | SCN9A (0.43) | SCN9ACYP19A1PTGS1PTGS2NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452936-A2 | INDOLES, INDAZOLES, AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | The Katholieke Universiteit Leuven (BE) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023122782-A2 | INDOLES, INDAZOLES, AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-06-29 | — | — | WO | disclosed |