Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 15/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 12/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25311117 | 1.00 | CD274 (0.38) | CD274PDCD1LG2PDCD1DDB1CRBN | |
| SCHEMBL25315591 | 1.00 | CD274 (0.38) | CD274PDCD1LG2PDCD1DDB1CRBN | |
| SCHEMBL30482532 | 1.00 | CD274 (0.38) | CD274PDCD1LG2PDCD1DDB1CRBN | |
| SCHEMBL25311371 | 0.86 | CD274 (0.36) | CD274PDCD1LG2PDCD1CRBN | |
| SCHEMBL25313884 | 0.86 | CD274 (0.36) | CD274PDCD1LG2PDCD1CRBN | |
| SCHEMBL25263109 | 0.79 | CD274 (0.37) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL25309676 | 0.79 | CD274 (0.37) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL25313699 | 0.79 | CD274 (0.38) | CD274PDCD1LG2PDCD1DDB1CRBN | |
| SCHEMBL25310838 | 0.79 | CD274 (0.38) | CD274PDCD1LG2PDCD1DDB1CRBN | |
| SCHEMBL25313374 | 0.77 | KCNA5 (0.40) | CD274PDCD1LG2PDCD1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116368112-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2023-06-30 | — | — | CN | disclosed |