Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 5/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29303971 | 0.86 | GRM4 (0.45) | GRM4NOTUMMTORDYRK1BDRD2 | |
| SCHEMBL20282340 | 0.83 | GRM4 (0.43) | GRM4NOTUMCYP2C9MTORDYRK1B | |
| SCHEMBL2047296 | 0.81 | EPHX2 (0.45) | CYP1A2CYP2C19EPHX2GAACYP46A1 | |
| SCHEMBL20282263 | 0.79 | NOTUM (0.40) | GRM4NOTUMMTORDYRK1BDRD2 | |
| SCHEMBL24352877 | 0.77 | CYP3A4 (0.43) | CYP3A4EPHX2CYP46A1ALDH1A1 | |
| SCHEMBL2045755 | 0.77 | MTOR (0.44) | CYP1A2CYP3A4CYP2C9CYP2C19MTOR | |
| SCHEMBL31149031 | 0.77 | MTOR (0.44) | CYP1A2CYP3A4CYP2C9CYP2C19MTOR | |
| SCHEMBL30332214 | 0.77 | PDE9A (0.41) | GRM4NOTUMEPHX2CYP46A1ALDH1A1 | |
| SCHEMBL5546869 | 0.76 | GRM4 (0.48) | GRM4NOTUMCYP1A2CYP2C9MTOR | |
| SCHEMBL3626706 | 0.76 | MAPT (0.50) | GRM4NOTUMMTORDYRK1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130043-A1 | MONOACYLGLYCEROL LIPASE INHIBITORS AND USE THEREOF FOR THE TREATMENT OF ANXIETY | PSY THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |