Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21411535 | 0.88 | KDM4E (0.63) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL538983 | 0.79 | KDM4E (0.61) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL29787090 | 0.79 | KDM4E (0.64) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL29212821 | 0.79 | KDM4E (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL3855611 | 0.79 | KDM4E (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL3855614 | 0.79 | KDM4E (0.68) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL31018783 | 0.78 | KDM4E (0.63) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL22384094 | 0.78 | KDM4E (0.67) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL31018781 | 0.78 | KDM4E (0.63) | KDM4EMAPTAPAF1POLBRECQL | |
| SCHEMBL839528 | 0.77 | KDM4E (0.68) | KDM4EMAPTAPAF1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4456900-A1 | RESPIRATORY STIMULANT PARENTERAL FORMULATIONS | Enalare Therapeutics Inc. (US) | 2024-11-06 | — | — | EP | disclosed |
| WO-2023129502-A1 | RESPIRATORY STIMULANT PARENTERAL FORMULATIONS | ENALARE THERAPEUTICS INC. (US) | 2023-07-06 | — | — | WO | disclosed |