Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 3/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14842338 | 1.00 | IKBKE (0.45) | IKBKETBK1SCN9ASCN5AP2RX3 | |
| SCHEMBL23147922 | 0.89 | ACACB (0.40) | IKBKETBK1SCN9ASCN5AACACB | |
| SCHEMBL13960219 | 0.86 | ACACB (0.46) | SCN9ASCN5AP2RX3ACACBHRH3 | |
| SCHEMBL13961215 | 0.85 | LOX (0.44) | IKBKETBK1SCN9ASCN5AP2RX3 | |
| SCHEMBL13662044 | 0.85 | SCN9A (0.44) | SCN9ASCN5AP2RX3SYKACACB | |
| SCHEMBL29483271 | 0.85 | LOX (0.44) | IKBKETBK1SCN9ASCN5AP2RX3 | |
| SCHEMBL17221104 | 0.84 | LOX (0.47) | SCN9ASCN5AP2RX3ACACBNAMPT | |
| SCHEMBL19068835 | 0.82 | SCN9A (0.43) | SCN9ASCN5AP2RX3SYKACACB | |
| SCHEMBL17229319 | 0.81 | SCN9A (0.42) | SCN9ASCN5AP2RX3SYKACACB | |
| SCHEMBL26090540 | 0.80 | SCN9A (0.57) | SCN9ASCN5AP2RX3SYKACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069700-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |