Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.50 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (2E)-Hexenoic Acid SCHEMBL23615 | 1.00 | — | — | |
| (2E)-Hexenoic Acid SCHEMBL27373174 | 1.00 | TSHR (0.50) | TSHRGABRR1GABRR2BLMGABRR3 | |
| (2Z)-Hexenoic Acid SCHEMBL3504637 | 1.00 | — | — | |
| (2E)-Hexenoic Acid SCHEMBL23614 | 1.00 | — | — | |
| (2E)-Hexenoic Acid SCHEMBL28766026 | 0.97 | TSHR (0.48) | TSHRGABRR1GABRR2BLMGABRR3 | |
| (2E)-Hexenoic Acid SCHEMBL7927817 | 0.97 | — | — | |
| (2E)-Hexenoic Acid SCHEMBL29017251 | 0.97 | TSHR (0.48) | TSHRGABRR1GABRR2BLMGABRR3 | |
| (2E)-Hexenoic Acid SCHEMBL10522058 | 0.97 | TSHR (0.48) | TSHRGABRR1GABRR2BLMGABRR3 | |
| (2E)-Hexenoic Acid SCHEMBL29041595 | 0.97 | TSHR (0.48) | TSHRGABRR1GABRR2BLMGABRR3 | |
| (2E)-Hexenoic Acid SCHEMBL28532321 | 0.97 | TSHR (0.48) | TSHRGABRR1GABRR2BLMGABRR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119559-A1 | Topically active agents to remove actinic keratoses and basal (BCC) and squamous (SCC) cell carcinomas using a combination of sulindac, its metabolites and derivatives with an oxidizing agent to generate reactive oxygen species nontoxic to normal cells; sulindac methionine sulfoxide/hydrogen peroxide | FLORIDA ATLANTIC UNIVERSITY (US) | 2008-05-22 | — | — | US | claimed |
| EP-1865972-A2 | TREATMENT OR PREVENTION OF CANCER AND PRECANCEROUS DISORDERS | FLORIDA ATLANTIC UNIVERSITY (US) | 2007-12-19 | — | — | EP | claimed |
| US-20060235080-A1 | Treatment or prevention of cancer and precancerous disorders | FLORIDA ATLANTIC UNIVERSITY (US) | 2006-10-19 | — | — | US | claimed |
| WO-2006102439-A2 | TREATMENT OR PREVENTION OF CANCER AND PRECANCEROUS DISORDERS | FLORIDA ATLANTIC UNIVERSITY (US) | 2006-09-28 | — | — | WO | claimed |
| CN-115087871-A | Fatty acid quantification device and method | 纽卓索斯医药和营养服务公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-108273478-B | Formaldehyde removal composition and product | 李怀玉 | 2021-03-02 | — | — | CN | disclosed |
| US-8765808-B2 | Treatment or prevention of cancer and precancerous disorders | CHS PHARMA, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-8603985-B2 | Treatment or prevention of cancer and precancerous disorders | CHS Pharma, Inc (US) | 2013-12-10 | — | — | US | disclosed |
| EP-1865972-B1 | TREATMENT OR PREVENTION OF CANCER AND PRECANCEROUS DISORDERS | CHS PHARMA INC (US) | 2013-11-06 | — | — | EP | disclosed |
| US-8357720-B2 | Treatment or prevention of cancer and precancerous disorders | FLORIDA ATLANTIC UNIVERSITY (US) | 2013-01-22 | — | — | US | disclosed |
| US-8258181-B2 | Topically active agents to remove actinic keratoses and basal (BCC) and squamous (SCC) cell carcinomas using a combination of sulindac, its metabolites and derivatives with an oxidizing agent to generate reactive oxygen species nontoxic to normal cells; sulindac methionine sulfoxide/hydrogen peroxide | FLORIDA ATLANTIC UNIVERSITY (US) | 2012-09-04 | — | — | US | disclosed |
| US-20100260864-A1 | TREATMENT OR PREVENTION OF CANCER AND PRECANCEROUS DISORDERS | FLORIDA ATLANTIC UNIVERSITY (US) | 2010-10-14 | — | — | US | disclosed |
| US-20100069331-A1 | TREATMENT OR PREVENTION OF CANCER AND PRECANCEROUS DISORDERS | FLORIDA ATLANTIC UNIVERSITY (US) | 2010-03-18 | — | — | US | disclosed |
| US-20080119559-A1 | Topically active agents to remove actinic keratoses and basal (BCC) and squamous (SCC) cell carcinomas using a combination of sulindac, its metabolites and derivatives with an oxidizing agent to generate reactive oxygen species nontoxic to normal cells; sulindac methionine sulfoxide/hydrogen peroxide | FLORIDA ATLANTIC UNIVERSITY (US) | 2008-05-22 | — | — | US | disclosed |
| EP-1865972-A2 | TREATMENT OR PREVENTION OF CANCER AND PRECANCEROUS DISORDERS | FLORIDA ATLANTIC UNIVERSITY (US) | 2007-12-19 | — | — | EP | disclosed |
| US-20060235080-A1 | Treatment or prevention of cancer and precancerous disorders | FLORIDA ATLANTIC UNIVERSITY (US) | 2006-10-19 | — | — | US | disclosed |
| WO-2006102439-A2 | TREATMENT OR PREVENTION OF CANCER AND PRECANCEROUS DISORDERS | FLORIDA ATLANTIC UNIVERSITY (US) | 2006-09-28 | — | — | WO | disclosed |
| WO-2003068324-A1 | ORGANIC CONTAMINANT REMOVAL FROM SLUDGE BY TARGETED CATALYSIS | MOTSENBOCKER MARVIN (US) | 2003-08-21 | — | — | WO | disclosed |
| US-5563132-A | Two-step cancer treatment method | BODANESS RICHARD S (US) | 1996-10-08 | — | — | US | disclosed |