Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 17/20 | 0.61 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.56 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.56 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21979498 | 1.00 | MAP2K1 (0.61) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| SCHEMBL26047206 | 0.91 | MAP2K1 (0.49) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| SCHEMBL24239396 | 0.91 | MAP2K1 (0.64) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| Nedometinib SCHEMBL21979494 | 0.85 | MAP2K1 (0.64) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| Nedometinib SCHEMBL29500231 | 0.85 | MAP2K1 (0.64) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| SCHEMBL21979505 | 0.85 | MAP2K1 (0.48) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL21979490 | 0.84 | MAP2K1 (0.44) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| SCHEMBL30486884 | 0.84 | MAP2K1 (0.44) | MAP2K1MAP2K2MAP2K5EIF2AK1KCNH2 | |
| Hydrochloric Acid SCHEMBL28385111 | 0.84 | MAP2K1 (0.48) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL22039975 | 0.81 | MAP2K1 (0.42) | MAP2K1MAP2K2MAP2K5EIF2AK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119215031-A | Arylaniline and heteroaryl aniline compounds for the treatment of skin cancer | 恩福莱克逊治疗有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-113645964-B | Arylaniline and heteroaryl aniline compounds for fetal treatment | 恩福莱克逊治疗有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-113660931-B | Arylaniline and heteroaryl aniline compounds for the treatment of skin cancer | 恩福莱克逊治疗有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-111065393-B | Pyrrolopyridine-anilines for the treatment of skin disorders | 恩福莱克逊治疗有限公司 | 2023-08-18 | — | — | CN | disclosed |