Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 9/20 | 0.61 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21542241 | 1.00 | GRM7 (0.61) | GRM7P2RX7TRPM8POLBLTB4R | |
| SCHEMBL21542240 | 1.00 | GRM7 (0.61) | GRM7P2RX7TRPM8POLBLTB4R | |
| SCHEMBL20166003 | 1.00 | GRM7 (0.61) | GRM7P2RX7TRPM8POLBLTB4R | |
| SCHEMBL20166004 | 1.00 | GRM7 (0.61) | GRM7P2RX7TRPM8POLBLTB4R | |
| SCHEMBL20166001 | 1.00 | GRM7 (0.61) | GRM7P2RX7TRPM8POLBLTB4R | |
| SCHEMBL21542298 | 0.91 | GRM7 (0.71) | GRM7P2RX7POLB | |
| SCHEMBL21542296 | 0.91 | GRM7 (0.71) | GRM7P2RX7POLB | |
| SCHEMBL20182784 | 0.91 | GRM7 (0.71) | GRM7P2RX7POLB | |
| SCHEMBL20165981 | 0.86 | GRM7 (0.75) | GRM7P2RX7TRPM8LTB4RLTB4R2 | |
| SCHEMBL20165979 | 0.86 | GRM7 (0.75) | GRM7P2RX7TRPM8LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541812-B1 | MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS | TAKEDA PHARMACEUTICALS CO (JP) | 2023-06-14 | — | — | EP | disclosed |