Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 9/20 | 0.66 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183016 | 1.00 | GRM7 (0.66) | GRM7P2RX7HTR2BPGRMEN1 | |
| SCHEMBL21542195 | 1.00 | GRM7 (0.66) | GRM7P2RX7HTR2BPGRMEN1 | |
| SCHEMBL21542196 | 1.00 | GRM7 (0.66) | GRM7P2RX7HTR2BPGRMEN1 | |
| SCHEMBL21542290 | 0.98 | GRM7 (0.66) | GRM7P2RX7HTR2BPGRMEN1 | |
| SCHEMBL21542288 | 0.98 | GRM7 (0.66) | GRM7P2RX7HTR2BPGRMEN1 | |
| SCHEMBL20182781 | 0.98 | GRM7 (0.66) | GRM7P2RX7HTR2BPGRMEN1 | |
| SCHEMBL20182845 | 0.92 | GRM7 (0.64) | GRM7P2RX7 | |
| SCHEMBL29909581 | 0.92 | GRM7 (0.64) | GRM7P2RX7 | |
| SCHEMBL21542311 | 0.92 | GRM7 (0.64) | GRM7P2RX7 | |
| SCHEMBL21542309 | 0.92 | GRM7 (0.64) | GRM7P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541812-B1 | MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS | TAKEDA PHARMACEUTICALS CO (JP) | 2023-06-14 | — | — | EP | disclosed |