SCHEMBL30487376

SCHEMBL30487376

CCSc1cc(N2CCc3cc(F)ccc3C2)cc(C)c1NC(=O)CC(C)(C)C

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNQ2 O43526 20/20 0.81
KCNQ3 O43525 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25245462 1.00 KCNQ2 (0.81) KCNQ2KCNQ3
SCHEMBL30487383 0.96 KCNQ2 (0.75) KCNQ2KCNQ3
SCHEMBL25289050 0.96 KCNQ2 (0.75) KCNQ2KCNQ3
SCHEMBL25288241 0.93 KCNQ2 (0.68) KCNQ2KCNQ3
SCHEMBL31020072 0.93 KCNQ2 (0.68) KCNQ2KCNQ3
SCHEMBL31546534 0.91 KCNQ2 (0.78) KCNQ2KCNQ3
SCHEMBL30487341 0.91 KCNQ2 (0.67) KCNQ2KCNQ3
SCHEMBL25286333 0.91 KCNQ2 (0.84) KCNQ2KCNQ3
SCHEMBL30487369 0.90 KCNQ2 (0.76) KCNQ2KCNQ3
Azetukalner SCHEMBL30429530 0.90 KCNQ2 (1.00) KCNQ2KCNQ3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119948023-A Regulator containing piperidine polycyclic derivative, preparation method and application thereof 上海翰森生物医药科技有限公司 2025-05-06 CN disclosed
CN-118451079-A Benzopiperidine derivative modulators, methods of preparation and uses thereof 上海翰森生物医药科技有限公司 2024-08-06 CN disclosed
WO-2023125935-A1 BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2023-07-06 WO disclosed