Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 17/20 | 0.57 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245688 | 1.00 | KCNQ2 (0.57) | KCNQ2KCNQ3JAK2JAK1TYK2 | |
| SCHEMBL25288208 | 0.93 | KCNQ2 (0.60) | KCNQ2KCNQ3JAK2JAK1TYK2 | |
| SCHEMBL31020014 | 0.93 | KCNQ2 (0.60) | KCNQ2KCNQ3JAK2JAK1TYK2 | |
| SCHEMBL31020000 | 0.91 | KCNQ2 (0.58) | KCNQ2KCNQ3 | |
| SCHEMBL25246149 | 0.91 | KCNQ2 (0.58) | KCNQ2KCNQ3 | |
| SCHEMBL25245159 | 0.91 | KCNQ2 (0.68) | KCNQ2KCNQ3 | |
| SCHEMBL30487318 | 0.91 | KCNQ2 (0.68) | KCNQ2KCNQ3 | |
| SCHEMBL25774664 | 0.90 | KCNQ2 (0.59) | KCNQ2KCNQ3 | |
| SCHEMBL25774658 | 0.87 | KCNQ2 (0.59) | KCNQ2KCNQ3 | |
| SCHEMBL25245042 | 0.86 | KCNQ2 (0.58) | KCNQ2KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948023-A | Regulator containing piperidine polycyclic derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-118451079-A | Benzopiperidine derivative modulators, methods of preparation and uses thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |