Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | USP7 | Q93009 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603599 | 1.00 | DYRK1A (0.61) | DYRK1AADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL6640763 | 0.81 | NPC1 (0.46) | DYRK1AMEN1KMT2AUSP7MAPT | |
| SCHEMBL7379292 | 0.80 | KDM4E (0.62) | DYRK1AADORA1ADORA2AMAPTALDH1A1 | |
| SCHEMBL5511069 | 0.80 | KDM4E (0.64) | DYRK1AADORA1ADORA2AMAPTALDH1A1 | |
| SCHEMBL12443814 | 0.80 | ADORA2A (0.73) | DYRK1AADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL11645510 | 0.79 | ADORA2A (0.79) | DYRK1AADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL14496829 | 0.78 | DYRK1A (0.54) | DYRK1AADORA1ADORA2AKMT2AMAPT | |
| SCHEMBL15757848 | 0.77 | AURKA (0.56) | DYRK1AADORA1ADORA2AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5542860 | 0.77 | DYRK1A (0.53) | DYRK1AADORA1ADORA2AKMT2AMAPT | |
| SCHEMBL1388722 | 0.76 | DYRK1A (1.00) | DYRK1AADORA1MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061116-B | Aminopyrimidine compound, preparation method, composition and application thereof | 上海医药工业研究院 | 2023-07-25 | — | — | CN | disclosed |