Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 7/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | MC3R | P41968 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21091967 | 1.00 | CASR (0.56) | CASRSLC6A4ADRA2CSLC6A2HTR2C | |
| SCHEMBL13077642 | 1.00 | CASR (0.56) | CASRSLC6A4ADRA2CSLC6A2HTR2C | |
| SCHEMBL28339998 | 1.00 | CASR (0.56) | CASRSLC6A4ADRA2CSLC6A2HTR2C | |
| SCHEMBL5473697 | 0.87 | CASR (0.57) | CASRSLC6A4ADRA2CSLC6A2HTR2C | |
| SCHEMBL5473700 | 0.87 | CASR (0.57) | CASRSLC6A4ADRA2CSLC6A2HTR2C | |
| SCHEMBL30842880 | 0.86 | CASR (0.54) | CASRSLC6A4ADRA2CSLC6A2HTR2C | |
| SCHEMBL7192331 | 0.86 | CASR (0.54) | CASRSLC6A4ADRA2CSLC6A2HTR2C | |
| SCHEMBL14428705 | 0.84 | CASR (0.55) | CASRSLC6A4ADRA2CSLC6A2HTR2C | |
| SCHEMBL13290807 | 0.84 | CASR (0.55) | CASRSLC6A4ADRA2CSLC6A2HTR2C | |
| SCHEMBL14228755 | 0.83 | CASR (0.57) | CASRSLC6A4ADRA2CSLC6A2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041220-B | Preparation method of aryl substituted amide compound | 浙江工业大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-116041220-A | Preparation method of aryl substituted amide compound | 浙江工业大学 | 2023-05-02 | — | — | CN | disclosed |