⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071294 | 0.62 | — | — | |
| SCHEMBL2699492 | 0.55 | — | — | |
| SCHEMBL31484759 | 0.52 | — | — | |
| SCHEMBL19327569 | 0.52 | — | — | |
| SCHEMBL27661124 | 0.52 | — | — | |
| SCHEMBL11335821 | 0.52 | — | — | |
| SCHEMBL9715235 | 0.51 | — | — | |
| SCHEMBL3767412 | 0.51 | — | — | |
| SCHEMBL28150095 | 0.50 | — | — | |
| SCHEMBL29666134 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7651997-B2 | Deoxo-proline-containing tamandarin and didemnin analogs, dehydro-proline-containing tamandarin and didemnin analogs, and methods of making and using them | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-01-26 | — | — | US | disclosed |
| US-20070129289-A1 | Deoxo-proline-containing tamandarin and didemnin analogs, dehydro-proline-containing tamandarin and didemnin analogs, and methods of making and using them | THE TRUSEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-06-07 | — | — | US | disclosed |
| EP-1276491-B9 | TAMANDARIN AND DIDEMNIN ANALOGS AND METHODS OF MAKING AND USING THEM | UNIV PENNSYLVANIA (US) | 2007-02-28 | — | — | EP | disclosed |
| EP-1276491-B1 | TAMANDARIN AND DIDEMNIN ANALOGS AND METHODS OF MAKING AND USING THEM | UNIV PENNSYLVANIA (US) | 2006-09-20 | — | — | EP | disclosed |
| US-7064105-B2 | Deoxo-proline-containing tamandarin and didemnin analogs, dehydro-proline-containing tamandarin and didemnin analogs, and methods of making and using them | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-06-20 | — | — | US | disclosed |
| EP-1276491-A4 | TAMANDARIN AND DIDEMNIN ANALOGS AND METHODS OF MAKING AND USING THEM | UNIV PENNSYLVANIA (US) | 2004-08-25 | — | — | EP | disclosed |
| EP-1276491-A1 | TAMANDARIN AND DIDEMNIN ANALOGS AND METHODS OF MAKING AND USING THEM | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2003-01-22 | — | — | EP | disclosed |
| US-20010056178-A1 | Deoxo-proline-containing tamandarin and didemnin analogs, dehydro-proline-containing tamandarin and didemnin analogs, and methods of making and using them | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-12-27 | — | — | US | disclosed |
| WO-2001076616-A1 | TAMANDARIN AND DIDEMNIN ANALOGS AND METHODS OF MAKING AND USING THEM | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2001-10-18 | — | — | WO | disclosed |