Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25650062 | 1.00 | CHRM2 (0.34) | CHRM2CHRM1CHRM3KLK7KDM4E | |
| SCHEMBL20788494 | 0.78 | KLK7 (0.36) | CHRM2CHRM1CHRM3KLK7KDM4E | |
| SCHEMBL5792537 | 0.78 | KLK7 (0.36) | CHRM2CHRM1CHRM3KLK7KDM4E | |
| SCHEMBL25650061 | 0.77 | DDB1 (0.32) | CHRM2CHRM1CHRM3KLK7 | |
| SCHEMBL25650019 | 0.77 | DDB1 (0.32) | CHRM2CHRM1CHRM3KLK7 | |
| SCHEMBL24020702 | 0.76 | PTPN1 (0.37) | CHRM2CHRM1CHRM3KLK7KDM4E | |
| SCHEMBL28926781 | 0.76 | PTPN1 (0.37) | CHRM2CHRM1CHRM3KLK7KDM4E | |
| SCHEMBL17113461 | 0.75 | CHRM2 (0.41) | CHRM2CHRM1CHRM3KDM4EMAPT | |
| SCHEMBL31133635 | 0.75 | CHRM2 (0.41) | CHRM2CHRM1CHRM3KDM4EMAPT | |
| SCHEMBL25650059 | 0.75 | CHRM2 (0.41) | CHRM2CHRM1CHRM3KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688156-A1 | LACTAM-CONTAINING IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201322-A1 | LACTAM-CONTAINING IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2024-10-03 | — | — | WO | disclosed |
| WO-2023111181-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-06-22 | — | — | WO | disclosed |