Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28405823 | 1.00 | TSHR (0.50) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL2118181 | 1.00 | TSHR (0.50) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL2119941 | 0.97 | — | — | |
| SCHEMBL1454894 | 0.90 | — | — | |
| SCHEMBL2936701 | 0.82 | TSHR (0.52) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL399787 | 0.82 | TSHR (0.52) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL104256 | 0.82 | TSHR (0.52) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL2998034 | 0.82 | TSHR (0.52) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL4052642 | 0.82 | TSHR (0.52) | TSHRALDH1A1USP2MAPTCYP3A4 | |
| SCHEMBL2326413 | 0.82 | TSHR (0.52) | TSHRALDH1A1USP2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114599710-B | Polyorganosiloxane, method for producing same, and thermally conductive silicone composition | 陶氏东丽株式会社 | 2023-07-07 | — | — | CN | disclosed |
| US-20220380550-A1 | ORGANOPOLYSILOXANE, METHOD OF PRODUCING THE SAME, AND THERMALLY CONDUCTIVE SILICONE COMPOSITION | DOW TORAY CO., LTD. (JP) | 2022-12-01 | — | — | US | disclosed |
| EP-4053190-A1 | ORGANOPOLYSILOXANE AND METHOD FOR PRODUCING SAME, AND HEAT-CONDUCTIVE SILICONE COMPOSITION | Dow Toray Co., Ltd. (JP) | 2022-09-07 | — | — | EP | disclosed |
| CN-114599710-A | Polyorganosiloxane, method for producing same, and thermally conductive silicone composition | 陶氏东丽株式会社 | 2022-06-07 | — | — | CN | disclosed |
| WO-2021085586-A1 | ORGANOPOLYSILOXANE AND METHOD FOR PRODUCING SAME, AND HEAT-CONDUCTIVE SILICONE COMPOSITION | ダウ・東レ株式会社 | 2021-05-06 | — | — | WO | disclosed |
| US-8138254-B2 | Thermally conductive silicone rubber composition | DOW CORNING TORAY COMPANY, LTD. (JP) | 2012-03-20 | — | — | US | disclosed |
| US-8093331-B2 | Thermally conductive silicone rubber composition | DOW CORNING TORAY COMPANY, LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-20110163460-A1 | Thermally Conductive Silicone Composition And Semiconductor Device | DOW CORNING TORAY CO., LTD. (JP) | 2011-07-07 | — | — | US | disclosed |
| US-20100140538-A1 | SILICONE ELASTOMER COMPOSITION AND SILICONE ELASTOMER | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-06-10 | — | — | US | disclosed |
| US-7622539-B2 | Organopolysiloxane and silicone composition | DOW CORNING TORAY COMPANY, LTD. (JP) | 2009-11-24 | — | — | US | disclosed |
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |
| US-5306719-A | Cardiotonic agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0255134-B1 | CARBOSTYRIL DERIVATIVES AND SALTS THEREOF, PROCESS FOR PREPARING THEM, AND CARDIOTONIC COMPOSITION CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5071856-A | CARBOSTYRIL DERIVATIVES AND SALTS THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| US-4886809-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| US-4845100-A | WITH HYPOTENSIVE AND ANTIINFLAMMATORY ACTIVITY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0255134-A2 | Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-03 | — | — | EP | disclosed |
| EP-0202760-A2 | Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-26 | — | — | EP | disclosed |