Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.73 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30489676 | 1.00 | SYK (0.73) | SYKCTRB1ATMMAPTCTSS | |
| SCHEMBL28668267 | 0.89 | SYK (0.74) | SYKCTRB1ATMMAPTCTSS | |
| SCHEMBL30489620 | 0.89 | SYK (0.74) | SYKCTRB1ATMMAPTCTSS | |
| SCHEMBL14497009 | 0.89 | SYK (0.74) | SYKCTRB1ATMMAPTCTSS | |
| SCHEMBL975349 | 0.89 | SYK (0.74) | SYKCTRB1ATMMAPTCTSS | |
| SCHEMBL6541785 | 0.89 | SYK (0.74) | SYKCTRB1ATMMAPTCTSS | |
| SCHEMBL28663877 | 0.88 | SYK (0.73) | SYKCTRB1ATMMAPTCTSS | |
| SCHEMBL27619888 | 0.88 | SYK (0.73) | SYKCTRB1ATMMAPTCTSS | |
| SCHEMBL14497012 | 0.88 | SYK (0.73) | SYKCTRB1ATMMAPTCTSS | |
| SCHEMBL30269165 | 0.87 | SYK (0.71) | SYKCTRB1ATMMAPTCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313828-B1 | METALLO-BETA-LACTAMASE INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-07-12 | — | — | EP | disclosed |