Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8155073 | 1.00 | — | — | |
| Bromide SCHEMBL18166523 | 1.00 | — | — | |
| Bromide SCHEMBL2687321 | 1.00 | — | — | |
| Bromide SCHEMBL11160094 | 1.00 | — | — | |
| Bromide SCHEMBL3054552 | 1.00 | — | — | |
| Bromide SCHEMBL9451029 | 0.87 | — | — | |
| Bromide SCHEMBL11503584 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8678783 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL10602065 | 0.82 | CA4 (0.50) | — | |
| Hydrochloric Acid SCHEMBL8706271 | 0.82 | CA4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100268003-A1 | PROCESS FOR INCREASING PURITY OF SOLID BROMINATED FLAME RETARDANTS DURING PREPARATION | ALBEMARLE CORPORATION (US) | 2010-10-21 | — | — | US | disclosed |
| WO-2009076056-A1 | PROCESS FOR INCREASING PURITY OF SOLID BROMINATED FLAME RETARDANTS DURING PREPARATION | ALBEMARLE CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |
| EP-1226189-B1 | METAL CONTAINING DISPERSANT POLYMERS FROM CONDENSATION OF POLYMERS CONTAINING ACIDIC GROUP WITH OVERBASED COMPOSITIONS CONTAINING REACTIVE NUCLEOPHILIC GROUP | LUBRIZOL CORP (US) | 2004-12-22 | — | — | EP | disclosed |
| EP-1226189-A1 | METAL CONTAINING DISPERSANT POLYMERS FROM CONDENSATION OF POLYMERS CONTAINING ACIDIC GROUP WITH OVERBASED COMPOSITIONS CONTAINING REACTIVE NUCLEOPHILIC GROUP | The Lubrizol Corporation (US) | 2002-07-31 | — | — | EP | disclosed |
| US-6403725-B1 | OIL ADDITIVES, ANTIDEPOSIT AGENTS | THE LUBRIZOL CORPORATION | 2002-06-11 | — | — | US | disclosed |
| WO-2001014433-A1 | METAL CONTAINING DISPERSANT POLYMERS FROM CONDENSATION OF POLYMERS CONTAINING ACIDIC GROUP WITH OVERBASED COMPOSITIONS CONTAINING REACTIVE NUCLEOPHILIC GROUP | THE LUBRIZOL CORPORATION (US) | 2001-03-01 | — | — | WO | disclosed |
| US-5883057-A | MINERAL OILS AND ADDITIVES FOR LUBRICATION | THE LUBRIZOL CORPORATION (US) | 1999-03-16 | — | — | US | disclosed |
| EP-0790294-A2 | Lubricating compositions | The Lubrizol Corporation (US) | 1997-08-20 | — | — | EP | disclosed |
| EP-0604408-B1 | Alpha-olefin polymers | LUBRIZOL CORP (US) | 1997-04-23 | — | — | EP | disclosed |
| US-5489721-A | ADDITION POLYMERIZATION IN PRESENCE OF SECONDARY ORGANOHALIDE AND A LEWIS ACID CATALYST MIXTURE TO FORM LIQUID POLYOLEFIN | THE LUBRIZOL CORPORATION (US) | 1996-02-06 | — | — | US | disclosed |
| US-5364994-A | Lubricating compositions containing α-olefin polymers | THE LUBRIZOL CORPORATION (US) | 1994-11-15 | — | — | US | disclosed |
| US-5345024-A | Addition polymerization using Lewis acid and tert-organo halide mixture catalyst system; viscosity improvers | THE LUBRIZOL CORPORATION (US) | 1994-09-06 | — | — | US | disclosed |
| EP-0604408-A1 | Alpha-olefin polymers | THE LUBRIZOL CORPORATION (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5302772-A | Addition polymerization of alpha olefins with organo halide and lewis acid catalyst | THE LUBRIZOL CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |
| US-5210362-A | Lewis acid catalyst for addition polymerization | THE LUBRIZOL CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0427839-A1 | ALPHA-OLEFIN POLYMERS. | LUBRIZOL CORP (US) | 1991-05-22 | — | — | EP | disclosed |
| WO-1990015080-A1 | ALPHA-OLEFIN POLYMERS | THE LUBRIZOL CORPORATION (US) | 1990-12-13 | — | — | WO | disclosed |
| US-4968853-A | VISCOSITY IMPROVERS FOR LUBRICANTS, POLYMODAL DISTRIBUTION | THE LUBRIZOL CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0349639-A1 | Process for preparing alpha-olefin polymers. | LUBRIZOL CORP (US) | 1990-01-10 | — | — | EP | disclosed |
| WO-1989006247-A2 | ALPHA-OLEFIN POLYMERS | THE LUBRIZOL CORPORATION (US) | 1989-07-13 | — | — | WO | disclosed |