SCHEMBL30490609

SCHEMBL30490609

CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.50
DPP7 Q9UHL4 4/20 0.50
DPP8 Q6V1X1 3/20 0.50
DPP9 Q86TI2 2/20 0.50
FAP Q12884 1/20 0.50
XIAP P98170 1/20 0.49
ELANE P08246 4/20 0.47
ACE P12821 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350414 0.92 XIAP (0.56) DPP4DPP7DPP8DPP9FAP
SCHEMBL30361566 0.92 DPP4 (0.44) DPP4DPP7DPP8DPP9FAP
SCHEMBL30490601 0.91 ACE (0.45) XIAPELANEACE
SCHEMBL30361563 0.90 NTSR2 (0.49) ELANEACE
SCHEMBL30490607 0.90 NTSR2 (0.49) ELANEACE
SCHEMBL30490571 0.89 ACE (0.47) DPP4DPP7DPP8DPP9FAP
SCHEMBL10702146 0.89 DPP4 (0.52) DPP4DPP7DPP8DPP9FAP
SCHEMBL10702151 0.89 DPP4 (0.52) DPP4DPP7DPP8DPP9FAP
SCHEMBL30490560 0.89 CALCRL (0.43) XIAPELANE
SCHEMBL30844376 0.87 ACE (0.59) DPP4DPP7DPP8DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4214221-A1 ANTIMICROBIAL PEPTIDOMIMETICS Spexis AG (CH) 2023-07-26 EP claimed
EP-4214221-A1 ANTIMICROBIAL PEPTIDOMIMETICS Spexis AG (CH) 2023-07-26 EP disclosed