Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 15/20 | 0.65 |
| ▸ | CDK2 | P24941 | 14/20 | 0.65 |
| ▸ | CCNA1 | P78396 | 14/20 | 0.65 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.65 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.55 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22466838 | 1.00 | FLT3 (0.65) | FLT3CDK2CCNA1STING1PBK | |
| SCHEMBL22466918 | 0.88 | FLT3 (0.64) | FLT3CDK2CCNA1STING1PBK | |
| SCHEMBL30490720 | 0.88 | FLT3 (0.64) | FLT3CDK2CCNA1STING1PBK | |
| SCHEMBL22477971 | 0.87 | FLT3 (0.68) | FLT3CDK2CCNA1STING1PBK | |
| SCHEMBL22478402 | 0.87 | FLT3 (0.68) | FLT3CDK2CCNA1STING1PBK | |
| SCHEMBL22477939 | 0.85 | FLT3 (0.76) | FLT3CDK2CCNA1STING1PBK | |
| SCHEMBL30490704 | 0.83 | FLT3 (0.63) | FLT3CDK2CCNA1STING1PBK | |
| SCHEMBL22467048 | 0.83 | FLT3 (0.63) | FLT3CDK2CCNA1STING1PBK | |
| SCHEMBL22466882 | 0.83 | FLT3 (0.72) | FLT3CDK2CCNA1STING1PBK | |
| SCHEMBL30490744 | 0.83 | FLT3 (0.72) | FLT3CDK2CCNA1STING1PBK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110662536-B | Kinase network inhibitors and uses thereof | 普渡研究基金会 | 2023-06-23 | — | — | CN | disclosed |