Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 3/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24149430 | 0.96 | CYP3A4 (0.34) | BTN3A1TMPRSS2CYP3A4CYP2C9RIPK1 | |
| SCHEMBL30269863 | 0.94 | BTN3A1 (0.37) | BTN3A1TMPRSS2CYP3A4CYP2C9RIPK1 | |
| SCHEMBL24149475 | 0.93 | BTN3A1 (0.33) | BTN3A1TMPRSS2CYP3A4CYP2C9RIPK1 | |
| SCHEMBL25014011 | 0.93 | CYP3A4 (0.33) | TMPRSS2CYP3A4CYP2C9 | |
| SCHEMBL25014009 | 0.93 | CYP3A4 (0.33) | TMPRSS2CYP3A4CYP2C9 | |
| SCHEMBL24149439 | 0.93 | TMPRSS2 (0.35) | BTN3A1TMPRSS2 | |
| SCHEMBL24149810 | 0.92 | CYP3A4 (0.33) | TMPRSS2CYP3A4CYP2C9 | |
| SCHEMBL25013959 | 0.92 | CYP3A4 (0.33) | TMPRSS2CYP3A4CYP2C9RIPK1 | |
| SCHEMBL24149835 | 0.92 | CYP3A4 (0.33) | TMPRSS2CYP3A4CYP2C9 | |
| SCHEMBL24149150 | 0.92 | CYP3A4 (0.33) | TMPRSS2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4172160-A2 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-05-03 | — | — | EP | disclosed |