SCHEMBL30493020

CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	TFPI	P10646	1/20	0.51

▸	OPRM1	P35372	1/20	0.49

▸	VIPR2	P41587	2/20	0.48

▸	NPY4R	P50391	3/20	0.48

▸	NPY1R	P25929	2/20	0.48

▸	NPY2R	P49146	2/20	0.48

▸	NPY5R	Q15761	2/20	0.48

▸	VIPR1	P32241	2/20	0.48

▸	IL23R	Q5VWK5	4/20	0.48

▸	BACE1	P56817	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30342387	0.91	TFPI (0.57)	TFPIVIPR2NPY4RNPY1RNPY2R
SCHEMBL29732500	0.90	NPY4R (0.56)	NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL11302814	0.90	NPY4R (0.50)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL11302796	0.90	NPY4R (0.50)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL29405934	0.89	ERAP2 (0.53)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL30371703	0.89	ERAP2 (0.53)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL30384921	0.88	BACE1 (0.56)	TFPINPY4RNPY1RNPY2RNPY5R
SCHEMBL30958066	0.88	NPY4R (0.56)	OPRM1NPY4RNPY1RNPY2RNPY5R
SCHEMBL30578951	0.88	BACE1 (0.55)	BACE1
SCHEMBL7867783	0.87	NPY4R (0.53)	NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230235374-A1	High Throughput Assays for Detecting Translation Readthrough Inducers	THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA	2023-07-27	—	—	US	disclosed