Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.47 |
| ▸ | WIZ | O95785 | 1/20 | 0.42 |
| ▸ | IKZF2 | Q9UKS7 | 6/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.39 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493456 | 0.91 | CRBN (0.53) | CRBNWIZIKZF2IKZF3DDB1 | |
| SCHEMBL29683622 | 0.85 | CRBN (0.63) | CRBNIKZF3DDB1 | |
| SCHEMBL25931822 | 0.84 | CRBN (0.55) | CRBNIKZF2IKZF3DDB1CSNK1A1 | |
| SCHEMBL25438464 | 0.83 | CRBN (0.52) | CRBNWIZIKZF2IKZF3ESR1 | |
| SCHEMBL30135762 | 0.82 | CRBN (0.58) | CRBNDDB1 | |
| SCHEMBL31204457 | 0.82 | CRBN (0.56) | CRBNWIZIKZF2IKZF3DDB1 | |
| SCHEMBL31547296 | 0.80 | CRBN (0.49) | CRBNWIZGSPT1 | |
| SCHEMBL30996489 | 0.80 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL30493287 | 0.79 | CRBN (0.53) | CRBNWIZIKZF2IKZF3DDB1 | |
| SCHEMBL25431405 | 0.79 | CRBN (0.53) | CRBNWIZIKZF2IKZF3DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466260-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | Astrazeneca AB (SE) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |