Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.57 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.57 |
| ▸ | NPY4R | P50391 | 3/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13563436 | 1.00 | ACE (0.57) | ACEGRIA1NPY4RPTPN2PTPN1 | |
| SCHEMBL13563434 | 0.95 | ACE (0.60) | ACEGNPAT | |
| SCHEMBL13563442 | 0.95 | ACE (0.60) | ACEGNPAT | |
| SCHEMBL13563439 | 0.95 | ACE (0.60) | ACEGNPAT | |
| SCHEMBL6518708 | 0.94 | ACE (0.55) | ACEGRIA1NPY4RPTPN2PTPN1 | |
| SCHEMBL468899 | 0.94 | ACE (0.55) | ACEGRIA1NPY4RPTPN2PTPN1 | |
| SCHEMBL30863541 | 0.93 | GRIA1 (0.54) | ACEGRIA1NPY4RPTPN2PTPN1 | |
| SCHEMBL30493794 | 0.92 | ACE (0.56) | ACEGRIA1NPY4RPTPN2PTPN1 | |
| SCHEMBL30493688 | 0.91 | NPY4R (0.59) | ACENPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL25627344 | 0.89 | BACE1 (0.55) | ACEGNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3777876-B1 | N-ACYLDIPEPTIDE DERIVATIVES AND THEIR USES | NEOSTRATA COMPANY INC (US) | 2023-08-09 | — | — | EP | claimed |
| EP-3777876-B1 | N-ACYLDIPEPTIDE DERIVATIVES AND THEIR USES | NEOSTRATA COMPANY INC (US) | 2023-08-09 | — | — | EP | disclosed |