Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | DAO | P14920 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.47 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29053567 | 1.00 | HSD17B10 (0.56) | HSD17B10HPGDALDH1A1MEN1USP2 | |
| SCHEMBL30494448 | 0.91 | HPGD (0.53) | HSD17B10HPGDALDH1A1MEN1USP2 | |
| SCHEMBL29053576 | 0.91 | HPGD (0.53) | HSD17B10HPGDALDH1A1MEN1USP2 | |
| SCHEMBL17136028 | 0.89 | HSD17B10 (0.64) | HSD17B10HPGDALDH1A1MEN1USP2 | |
| SCHEMBL29053564 | 0.88 | HPGD (0.53) | HSD17B10HPGDALDH1A1MEN1USP2 | |
| SCHEMBL29053572 | 0.87 | HPGD (0.50) | HSD17B10HPGDALDH1A1MEN1USP2 | |
| SCHEMBL30494431 | 0.87 | HPGD (0.50) | HSD17B10HPGDALDH1A1MEN1USP2 | |
| SCHEMBL1145013 | 0.85 | HPGD (0.60) | HSD17B10HPGDALDH1A1MEN1USP2 | |
| SCHEMBL30494310 | 0.83 | HSD17B10 (0.58) | HSD17B10HPGDALDH1A1MEN1USP2 | |
| SCHEMBL30494411 | 0.83 | HSD17B10 (0.58) | HSD17B10HPGDALDH1A1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396284-B | Benzo-seven-membered nitrogen-oxygen heterocyclic indole-2-carboxamide derivative, preparation method and application thereof | 宁夏医科大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-116396284-A | Benzo-seven-membered nitrogen-oxygen heterocyclic indole-2-carboxamide derivative, preparation method and application thereof | 宁夏医科大学 | 2023-07-07 | — | — | CN | disclosed |