SCHEMBL30495391

SCHEMBL30495391

CCOC(=O)CC1(O)CCC(c2ccnc3ccc(F)cc23)CC1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.48
CYP2C9 P11712 4/20 0.47
CYP2C8 P10632 3/20 0.47
TDO2 P48775 3/20 0.47
CHRNA1 P02708 1/20 0.47
CYP2C19 P33261 1/20 0.47
CYP3A4 P08684 1/20 0.47
KCNH2 Q12809 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21213988 1.00 IDO1 (0.48) IDO1CYP2C9CYP2C8TDO2CHRNA1
SCHEMBL22387405 0.86 IDO1 (0.45) IDO1CYP2C9CYP2C8TDO2CHRNA1
SCHEMBL22270710 0.86 IDO1 (0.45) IDO1CYP2C9CYP2C8TDO2CHRNA1
SCHEMBL17729179 0.85 NR3C2 (0.45) IDO1
SCHEMBL17729264 0.85 NR3C2 (0.45) IDO1
SCHEMBL17729263 0.85 NR3C2 (0.45) IDO1
SCHEMBL21213986 0.85 IDO1 (0.50) IDO1CYP2C9CYP2C8TDO2CHRNA1
SCHEMBL17740952 0.83 IDO1 (0.51) IDO1CYP2C9CYP2C8TDO2CHRNA1
SCHEMBL22809022 0.83 IDO1 (0.51) IDO1CYP2C9CYP2C8TDO2CHRNA1
SCHEMBL17741077 0.83 IDO1 (0.51) IDO1CYP2C9CYP2C8TDO2CHRNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110092750-B Pentafluoro sulfanyl substituted amide compound, preparation method and application thereof in medicine 北京诺诚健华医药科技有限公司 2023-07-21 CN disclosed