SCHEMBL30495587

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)O)C(C)C)C(C)C)[C@@H](C)O

nearest known ligand 0.65

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	13/20	0.65

▸	VIPR2	P41587	2/20	0.62

▸	CALCR	P30988	3/20	0.62

▸	CCKBR	P32239	1/20	0.62

▸	VIPR1	P32241	2/20	0.61

▸	SCTR	P47872	1/20	0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30607312	0.93	GLP1R (0.60)	GLP1RVIPR2CALCRCCKBRVIPR1
SCHEMBL29939727	0.93	GLP1R (0.72)	GLP1RCALCRCCKBRVIPR1
SCHEMBL30970990	0.93	GLP1R (0.71)	GLP1RVIPR2CALCRCCKBRVIPR1
SCHEMBL29939655	0.92	GLP1R (0.70)	GLP1RCALCRCCKBRVIPR1
SCHEMBL31098050	0.92	CALCR (0.65)	GLP1RCALCR
SCHEMBL31182481	0.91	GLP1R (0.68)	GLP1RVIPR2VIPR1SCTR
SCHEMBL31603933	0.91	GLP1R (0.69)	GLP1RVIPR2VIPR1SCTR
SCHEMBL29600136	0.90	GLP1R (0.69)	GLP1RCALCRCCKBRVIPR1
SCHEMBL30432505	0.90	GLP1R (0.66)	GLP1RCALCRCCKBRVIPR1SCTR
SCHEMBL29520076	0.90	GLP1R (0.67)	GLP1RCALCRCCKBRSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230190887-A1	TARGETING G3BP AGGREGATION TO PREVENT NEURODEGENERATION	UNIVERSITY OF SOUTH CAROLINA (US)	2023-06-22	—	—	US	disclosed