SCHEMBL30495684

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(=O)O)C(C)C)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)O)[C@@H](C)O

nearest known ligand 0.70

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	20/20	0.70

▸	ECE1	P42892	1/20	0.65

▸	MUS81	Q96NY9	1/20	0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30118955	0.96	GLP1R (0.71)	GLP1RECE1MUS81
SCHEMBL31182714	0.94	GLP1R (0.67)	GLP1R
SCHEMBL30804649	0.93	GLP1R (0.70)	GLP1R
SCHEMBL31182950	0.92	GLP1R (0.72)	GLP1RECE1MUS81
SCHEMBL30658384	0.92	RXFP1 (0.71)	GLP1R
SCHEMBL30658325	0.92	RXFP1 (0.69)	GLP1RECE1MUS81
SCHEMBL31664370	0.91	RXFP1 (0.68)	GLP1RECE1MUS81
SCHEMBL29431871	0.91	GLP1R (0.84)	GLP1R
SCHEMBL31099271	0.91	GLP1R (0.84)	GLP1R
SCHEMBL28662518	0.91	GLP1R (0.84)	GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230190887-A1	TARGETING G3BP AGGREGATION TO PREVENT NEURODEGENERATION	UNIVERSITY OF SOUTH CAROLINA (US)	2023-06-22	—	—	US	disclosed