SCHEMBL30495752

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CN)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)CC)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	17/20	0.67

▸	ECE1	P42892	1/20	0.67

▸	MUS81	Q96NY9	1/20	0.67

▸	CCKBR	P32239	1/20	0.64

▸	PTH1R	Q03431	1/20	0.63

▸	GCGR	P47871	1/20	0.62

▸	GIPR	P48546	1/20	0.62

▸	IL23R	Q5VWK5	1/20	0.62

▸	KISS1R	Q969F8	1/20	0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31047778	0.92	GLP1R (0.78)	GLP1RECE1MUS81CCKBRGCGR
SCHEMBL30261989	0.91	GLP1R (0.64)	GLP1RECE1MUS81CCKBRPTH1R
SCHEMBL30906527	0.90	GLP1R (0.69)	GLP1RECE1MUS81CCKBRPTH1R
SCHEMBL31683311	0.90	GLP1R (0.67)	GLP1RECE1MUS81CCKBRGCGR
SCHEMBL30726557	0.90	GLP1R (0.70)	GLP1RECE1MUS81CCKBRGCGR
SCHEMBL31000903	0.90	GLP1R (0.71)	GLP1RECE1MUS81CCKBRPTH1R
SCHEMBL30979198	0.90	GLP1R (0.75)	GLP1RECE1MUS81CCKBRGCGR
SCHEMBL31499105	0.90	GLP1R (0.69)	GLP1RECE1MUS81CCKBRPTH1R
SCHEMBL30906498	0.89	GLP1R (0.69)	GLP1RECE1MUS81CCKBRPTH1R
SCHEMBL30906364	0.89	GLP1R (0.69)	GLP1RECE1MUS81CCKBRPTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230190887-A1	TARGETING G3BP AGGREGATION TO PREVENT NEURODEGENERATION	UNIVERSITY OF SOUTH CAROLINA (US)	2023-06-22	—	—	US	disclosed