Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.54 |
| ▸ | KHK | P50053 | 2/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.49 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713954 | 1.00 | PARP1 (0.54) | PARP1KHKTNKS2QTRT1TNKS | |
| SCHEMBL25362191 | 0.91 | PARP1 (0.52) | PARP1KHKTNKS2QTRT1TNKS | |
| SCHEMBL28004053 | 0.91 | PARP1 (0.62) | PARP1TNKS2QTRT1TNKSROCK2 | |
| SCHEMBL16404341 | 0.91 | PARP1 (0.62) | PARP1TNKS2QTRT1TNKSROCK2 | |
| SCHEMBL28501122 | 0.88 | PARP1 (0.58) | PARP1TNKS2QTRT1TNKSROCK2 | |
| SCHEMBL28507693 | 0.88 | PARP1 (0.56) | PARP1TNKS2QTRT1TNKSKMT2A | |
| SCHEMBL28113245 | 0.86 | PARP1 (0.55) | PARP1TNKS2QTRT1TNKS | |
| SCHEMBL29499006 | 0.86 | PARP1 (0.55) | PARP1TNKS2QTRT1TNKS | |
| SCHEMBL25362490 | 0.84 | PARP1 (0.52) | PARP1KHKTNKS2TNKS | |
| SCHEMBL30176907 | 0.84 | PARP1 (0.53) | PARP1TNKS2QTRT1TNKSROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674841-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2026-01-07 | — | — | EP | disclosed |
| CN-118973578-A | Pharmaceutical compounds | 杜克街生物有限公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-4444305-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |