Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 9/20 | 0.44 |
| ▸ | MERTK | Q12866 | 11/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499521 | 0.92 | TYRO3 (0.43) | TYRO3MERTKAXLBTK | |
| SCHEMBL30499548 | 0.88 | TYRO3 (0.41) | TYRO3MERTKAXLBTK | |
| SCHEMBL30499563 | 0.88 | TYRO3 (0.44) | TYRO3MERTKAXLBTK | |
| SCHEMBL30499519 | 0.87 | TYRO3 (0.44) | TYRO3MERTKAXLBTK | |
| SCHEMBL30499552 | 0.85 | MERTK (0.40) | TYRO3MERTKAXLBTK | |
| SCHEMBL30499489 | 0.83 | TYRO3 (0.48) | TYRO3MERTKAXL | |
| SCHEMBL30499530 | 0.81 | TYRO3 (0.45) | TYRO3MERTKAXLBTK | |
| SCHEMBL30367099 | 0.81 | TYRO3 (0.68) | TYRO3MERTKAXL | |
| SCHEMBL29052478 | 0.81 | TYRO3 (0.68) | TYRO3MERTKAXL | |
| SCHEMBL30499515 | 0.80 | TYRO3 (0.41) | TYRO3MERTKAXLBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |