Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.65 |
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | CASP3 | P42574 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.61 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25195367 | 1.00 | SMN1; SMN2 (0.65) | SMN1; SMN2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL914016 | 0.79 | SMN1; SMN2 (0.77) | SMN1; SMN2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL912737 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL914037 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL914213 | 0.77 | SMN1; SMN2 (0.77) | SMN1; SMN2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL913600 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL913965 | 0.76 | SMN1; SMN2 (0.72) | SMN1; SMN2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL913313 | 0.75 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL914596 | 0.75 | MAPT (0.77) | SMN1; SMN2MAPTALDH1A1HPGDRAB9A | |
| SCHEMBL3916315 | 0.74 | SMN1; SMN2 (0.76) | SMN1; SMN2MAPTALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323578-A | Thiophene HSD17B13 inhibitor and application thereof | 伊尼制药公司 | 2023-06-23 | — | — | CN | disclosed |