Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30501981 | 0.85 | BRD4 (0.48) | BRD4SMN1; SMN2DCTPP1TNF | |
| SCHEMBL18372654 | 0.79 | TNF (0.47) | BRD4SMN1; SMN2PTGER1MEN1KMT2A | |
| SCHEMBL30501926 | 0.79 | TNF (0.47) | BRD4SMN1; SMN2PTGER1MEN1KMT2A | |
| Dimethylamine SCHEMBL4774301 | 0.78 | TOP2A (0.40) | MEN1KMT2ATOP2A | |
| SCHEMBL7965582 | 0.76 | TNF (0.55) | BRD4MEN1KMT2ADCTPP1TNF | |
| SCHEMBL4666497 | 0.76 | BRD4 (0.47) | BRD4SMN1; SMN2HDAC1HDAC6SMPD1 | |
| SCHEMBL5901935 | 0.75 | HPGD (0.51) | SMN1; SMN2MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL31513743 | 0.73 | F2 (0.46) | BRD4KMT2ADCTPP1HDAC1HDAC6 | |
| SCHEMBL16371378 | 0.73 | TSHR (0.46) | SMN1; SMN2DCTPP1TNF | |
| SCHEMBL16371738 | 0.73 | TSHR (0.46) | SMN1; SMN2KMT2ADCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527272-B | Synthetic method of tergolian prazan | 西安淳甄新材料有限公司 | 2023-07-21 | — | — | CN | disclosed |