Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 18/20 | 0.35 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30502011 | 1.00 | KRAS (0.35) | KRASHAVCR2TRPV1 | |
| SCHEMBL30762757 | 0.85 | MAPK13 (0.39) | KRASHAVCR2TRPV1 | |
| SCHEMBL20560733 | 0.85 | MAPK13 (0.39) | KRASHAVCR2TRPV1 | |
| SCHEMBL23234780 | 0.85 | KRAS (0.36) | KRAS | |
| SCHEMBL21542680 | 0.80 | KRAS (0.39) | KRASHAVCR2TRPV1 | |
| SCHEMBL30762709 | 0.80 | KRAS (0.39) | KRASHAVCR2TRPV1 | |
| SCHEMBL23234859 | 0.78 | KRAS (0.40) | KRASTRPV1 | |
| SCHEMBL21543288 | 0.78 | MAPK13 (0.38) | KRASTRPV1 | |
| SCHEMBL30762794 | 0.78 | MAPK13 (0.38) | KRASTRPV1 | |
| SCHEMBL21542783 | 0.76 | KRAS (0.38) | KRASTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113248521-B | K-RAS G12C inhibitor and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-07-18 | — | — | CN | disclosed |