Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.49 |
| ▸ | IL6 | P05231 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22347078 | 1.00 | TLR7 (0.49) | TLR7IL6ADORA2AADORA2BADORA1 | |
| SCHEMBL26348185 | 0.90 | TLR7 (0.49) | TLR7IL6CA12CA1CA2 | |
| SCHEMBL22347110 | 0.83 | TLR7 (0.48) | TLR7IL6ADORA2AADORA2BCA12 | |
| SCHEMBL30503456 | 0.83 | TLR7 (0.48) | TLR7IL6ADORA2AADORA2BCA12 | |
| SCHEMBL29034570 | 0.83 | TLR7 (0.50) | TLR7IL6 | |
| SCHEMBL26348207 | 0.81 | ADORA2A (0.41) | TLR7ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL31124769 | 0.79 | TLR7 (0.47) | TLR7IL6 | |
| SCHEMBL26348191 | 0.79 | ADORA2A (0.55) | TLR7ADORA2AADORA2BADORA1 | |
| SCHEMBL22359663 | 0.79 | ADORA2A (0.39) | TLR7ADORA2AADORA2BADORA1 | |
| SCHEMBL31398561 | 0.78 | TLR7 (0.50) | TLR7IL6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |