Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 6/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30397534 | 0.77 | CES1 (0.55) | CES1KDM4EMAOAMAOBTGM2 | |
| SCHEMBL281586 | 0.77 | CES1 (0.55) | CES1KDM4EMAOAMAOBTGM2 | |
| SCHEMBL30536407 | 0.76 | MAPT (0.46) | GRIA1CACNG8 | |
| SCHEMBL6179037 | 0.74 | CES1 (0.55) | CES1HTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL3063162 | 0.73 | CES1 (0.58) | CES1GRIA1CACNG8KDM4EMAOA | |
| SCHEMBL5894111 | 0.73 | CES1 (0.50) | CES1HTR2AHTR2CHTR2BMAOA | |
| SCHEMBL4625091 | 0.73 | CES1 (0.50) | CES1HTR2AKDM4EMAOAMAOB | |
| SCHEMBL20526943 | 0.71 | CES1 (0.53) | CES1GRIA1CACNG8HTR2AHTR2C | |
| SCHEMBL4242823 | 0.71 | CES1 (0.60) | CES1MAOAMAOBTGM2CA1 | |
| SCHEMBL18703103 | 0.70 | MAOB (0.52) | CES1KDM4EMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535619-A | Preparation method and application of high molecular weight arylene isatin polymer and ionic solvent film | 宁波中科氢易膜科技有限公司 | 2023-08-04 | — | — | CN | disclosed |