Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 18/20 | 0.71 |
| ▸ | PDCD1 | Q15116 | 17/20 | 0.71 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30504452 | 0.91 | CD274 (0.63) | CD274PDCD1TLR9TLR7APEX1 | |
| SCHEMBL19549706 | 0.83 | CD274 (1.00) | CD274PDCD1TLR9TLR7 | |
| SCHEMBL30504422 | 0.81 | CD274 (0.68) | CD274PDCD1TLR9TLR7APEX1 | |
| SCHEMBL19549722 | 0.74 | PDCD1 (0.82) | CD274PDCD1 | |
| SCHEMBL12491614 | 0.70 | PDCD1 (0.69) | CD274PDCD1TLR9TLR7APEX1 | |
| SCHEMBL20324274 | 0.70 | PDCD1 (0.66) | CD274PDCD1TLR9TLR7APEX1 | |
| SCHEMBL19549737 | 0.68 | PDCD1 (1.00) | CD274PDCD1TLR9TLR7APEX1 | |
| SCHEMBL19549702 | 0.67 | PDCD1 (0.70) | CD274PDCD1TLR9TLR7APEX1 | |
| SCHEMBL19549801 | 0.67 | PDCD1 (0.58) | CD274PDCD1TLR9TLR7 | |
| SCHEMBL19549760 | 0.67 | CD274 (0.71) | CD274PDCD1TLR9TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793077-B | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 东莞市东阳光新药研发有限公司 | 2023-08-04 | — | — | CN | disclosed |