Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116643 | 1.00 | USP2 (0.44) | USP2LMNAGRM5TUBB4ATUBB | |
| SCHEMBL20116956 | 0.87 | USP2 (0.41) | USP2LMNAGRM5TUBB4ATUBB | |
| SCHEMBL22358101 | 0.86 | MAPT (0.51) | USP2LMNAGRM5TUBB4ATUBB | |
| SCHEMBL22357823 | 0.84 | SMN1; SMN2 (0.41) | LMNAGRM5TUBB4ATUBBTUBA3C | |
| SCHEMBL22357966 | 0.83 | SMN1; SMN2 (0.42) | LMNAGRM5TUBB4ATUBBTUBA3C | |
| SCHEMBL22357808 | 0.80 | GRM5 (0.42) | GRM5TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22357847 | 0.80 | GRM5 (0.42) | GRM5TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22358226 | 0.80 | GRM5 (0.42) | GRM5TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20116106 | 0.80 | GRM5 (0.47) | GRM5TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20116104 | 0.80 | GRM5 (0.47) | GRM5TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |