Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 6/20 | 0.43 |
| ▸ | SMO | Q99835 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116591 | 1.00 | TSHR (0.43) | TSHRSMN1; SMN2NPC1GRM5SMO | |
| SCHEMBL20116106 | 0.89 | GRM5 (0.47) | TSHRSMN1; SMN2NPC1GRM5HSD11B1 | |
| SCHEMBL30506344 | 0.89 | GRM5 (0.47) | TSHRSMN1; SMN2NPC1GRM5HSD11B1 | |
| SCHEMBL30506241 | 0.89 | GRM5 (0.47) | TSHRSMN1; SMN2NPC1GRM5HSD11B1 | |
| SCHEMBL20116104 | 0.89 | GRM5 (0.47) | TSHRSMN1; SMN2NPC1GRM5HSD11B1 | |
| SCHEMBL20116103 | 0.89 | GRM5 (0.47) | TSHRSMN1; SMN2NPC1GRM5HSD11B1 | |
| SCHEMBL20116711 | 0.87 | TSHR (0.44) | TSHRSMN1; SMN2NPC1GRM5SMO | |
| SCHEMBL30506351 | 0.85 | GRM5 (0.47) | TSHRSMN1; SMN2NPC1GRM5HSD11B1 | |
| SCHEMBL20116503 | 0.85 | GRM5 (0.47) | TSHRSMN1; SMN2NPC1GRM5HSD11B1 | |
| SCHEMBL22358157 | 0.82 | GRM5 (0.51) | TSHRSMN1; SMN2GRM5TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |