Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116112 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2PREPMAPTPOLBLDHA | |
| SCHEMBL20116462 | 0.86 | SMO (0.57) | SMN1; SMN2LDHASMOKMT2A | |
| SCHEMBL30720960 | 0.86 | SMO (0.57) | SMN1; SMN2LDHASMOKMT2A | |
| SCHEMBL20661039 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2LDHASMOP2RY12KMT2A | |
| SCHEMBL20116128 | 0.84 | TLR8 (0.59) | SMN1; SMN2PREPMAPTPOLBTLR9 | |
| SCHEMBL30506325 | 0.83 | MAPT (0.51) | SMN1; SMN2PREPMAPTPOLBLDHA | |
| SCHEMBL20116116 | 0.83 | MAPT (0.51) | SMN1; SMN2PREPMAPTPOLBLDHA | |
| SCHEMBL22357815 | 0.83 | PREP (0.53) | SMN1; SMN2PREPMAPTPOLBLDHA | |
| SCHEMBL22358095 | 0.82 | SMO (0.53) | SMN1; SMN2POLBLDHASMOTLR9 | |
| SCHEMBL22357830 | 0.81 | SMO (0.52) | SMN1; SMN2LDHASMOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |